Dengue Virus type 3 RNA-dependent RNA polymerase versus inhibitors
收藏NIAID Data Ecosystem2026-05-10 收录
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Dengue Virus type 3 RNA-dependent RNA polymerase versus inhibitors
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2025-10-21
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Figure S1 - Peptide Inhibitors of Dengue-Virus Entry Target a Late-Stage Fusion Intermediate
Binding of stem-derived peptides with DV2 sE(1–395). Binding of sE to streptavidin beads in the presence of biotinylated DV2419–447. Peptide was added at the concentration shown to 2.5 µg sE dimer or
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Inhibitory profiles of N-pocket compounds in DENV polymerase with resistant phenotype amino acid changes.
Inhibitory profiles of N-pocket compounds in DENV polymerase with resistant phenotype amino acid changes.
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Dengue 3 NS5 protein with compound 29
Dengue 3 NS5 protein with compound 29 Descriptor: 1,2-ETHANEDIOL, 5-[5-(3-hydroxyprop-1-yn-1-yl)thiophen-2-yl]-4-methoxy-2-methyl-N-[(quinolin-8-yl)sulfonyl]benzamide, DI(HYDROXYETHYL)ETHER, ... Autho
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Discovery of a small molecule inhibitor targeting dengue virus NS5 RNA-dependent RNA polymerase
Dengue is a mosquito-borne viral infection that has spread globally in recent years. Around half of the world’s population, especially in the tropics and subtropics, is at risk of infection. Every yea
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Lucidone suppresses dengue viral replication through the induction of heme oxygenase-1
Dengue virus (DENV) infection causes life-threatening diseases such as dengue hemorrhagic fever and dengue shock syndrome. Currently, there is no effective therapeutic agent or vaccine against DENV in
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