five

Remodeling of white fat during browning involves YBX1 to drive thermogenic commitment

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP257862
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资源简介:
Effects of YBX1 activation in PPAR?-indcuded C3H/10T1/2-SAM pre-adipocytes on the transcriptome of cells during early differentation stages Overall design: C3H/10T1/2-SAM pre-adipocytes containing dCas9-VP64 and MS2-P65-HSF1 were transfected with guide RNA taregting PPAR? or a combination of guides taregting PPAR? and YBX1 two days before differentiation start to model gain of funtion in pre-adipocytes. Transcriptome was analysed for day 0, day 2 and day 4 of differentiation.
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2021-01-12
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