Transcriptomic profiling of CDCP1 knock-down in human cardiac fibroblasts (HCFs)

To investigate the function of CDCP1 in regulation of HCF proliferation, we cultured primary HCFs and transfected with non-targeting siRNA and CDCP1 siRNAs. Total RNA samples were extracted for RNA-seq to identify transcriptome-wide gene expression changes in the HCFs after CDCP1 knock-down (KD). Comparative gene expression profiling analysis of RNA-seq data for HCF cells with and wihout CDCP1 KD.