Steered Molecular Dynamics (SMD) simulations of the following system in explicit water: ETS domain; dsDNA with nucleotide sequences 5’-AAAAAAGGAAGGTGG-3’, and neutralized with 150 mM NaCl performed wi
Mutations in the histone 3 variant H3.3 have been identified in one-third of pediatric glioblastomas (GBMs), but not in adult tumors. Here we show that H3.3 is a dynamic determinant of functional prop
In meiosis, an excess number of DNA double-strand breaks (DSBs), the initiating DNA lesion, is formed compared to the number of crossovers, one of their repair products that creates the physical links
