Dataset for "Ab initio reconstruction of small angle scattering data for membrane proteins in copolymer nanodiscs"

The purpose behind this dataset is to investigate the use of form-factor based SANS fitting methods and compare them to dummy-models generated using the ab initio modelling tools. The paper focusses on two different membrane proteins, outer membrane protein F (OmpF) and gramicidin incorporated into polymer nanodiscs with styene maleic acid (SMA). These constructs were compared to other techniques (DLS and CD) to discuss the differences that arise from investigating these complex systems using various methods. These were also compared to known crystal structures.

This dataset holds the raw data files for the paper titled: "Ab initio reconstruction of small angle scattering data for membrane proteins in copolymer nanodiscs". Techniques include; size exclusion chromatography (SEC) for purification prior to other techniques; circular dichroism (CD); dynamic light scattering (DLS); small angle neutron scattering (SANS) and ab initio modelling constructs.