Growth of human CEM cell xenografts in SCID mice fed DIM or I3C.

Note: **, p<0.01 as determined by two-way ANOVA with Dunnett's post-hoc test comparisons for significant effect of experimental diet compared to the time-matched control (day 28 values for tumor volume are shown). ##, p<0.01 or ###, p<0.001 as determined by one-way ANOVA with Dunnett's post-hoc test comparisons for significant effects of experimental diets compared to control. †Tumor growth rates were modeled by non-linear regression analyses using the exponential growth equation with least-squares fit (Prism 5). Average doubling time (DT) values are shown and were calculated as follows: DT = [(To−Ti)×ln2]/ln(Vo/Vi) where Ti and To represent the initial and final time points and Vi and Vo represent initial and final tumor volumes. p-values (extra sum of squares F test) are reported for comparison of calculated growth curves for indicated treatments compared to control diet.