C. elegans and human genome releases underlying orthology prediction programs.
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KOG and TreeFam [22], [23] were not included in the meta-analysis used to generate OrthoList. KOG is shown for historical perspective, while TreeFam was used to confirm, or refute, orthology assignments. InParanoid, OrthoMCL, HomoloGene and Ensembl Compara [4], [19]–[21] were used to generate OrthoList.aFor the KOG database, the number of reported proteins analyzed includes alternatively-spliced forms derived from a single gene. For the other methods typically a single (the longest) isoform was used in the analysis.
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2015-12-02



