Respiratory pattern and apnea in Ndn−/− young adult versus Ndn+m/−p mice.

While the mean apnea duration was similar between genotypes (∼900 msec), evaluation of the total apnea duration expressed as the total recording time (i.e. apnea scores) revealed a two-fold increase in the percentage of total apnea duration in Ndn−/− compared to Ndn+m/−p individuals.Values are represented as Mean±SD; n = 20 for Ndn+m/−p and 18 for Ndn −/− mice.Mann Whitney t-test, two-tailed. P value = 0.02 (a) and 0.03 (b).