Global functional configurations in the nets formed by twelve subsystems.

In the DMNs different functional reactive structures may emerge spontaneously: all the subsystems are always in an on state, all the subsystems are always in an on-off changeable state, a certain number of metabolic subsystems are always locked in an on active state (metabolic core) while the rest of the subsystems remain in an on-off changing dynamics and nets in which all their subsystems are always off (nets functionally non-viable). It is shown in bold the set of nets in which a metabolic core emerges. β: the past influence coefficient. δ: the level of the enzymatic covalent regulatory activity (threshold value).