Phenotypical states modulate sensitivity and transcriptional reprogramming in patient-derived glioblastoma cells in response to temozolomide and radiation therapy. [RNA-Seq]

Differential molecular response involving epigenetic, transcriptomic and proteomic adaptstions of glioblastoma cancer stem-like cells and serum differentiaed cells in response to temozolomide and ionizing radiation Patient derived glioblastoma cancer stem-like cells and 2% FBS differentiated cells exposed to ionizing radiation (4 Gy) and temozolomide with corresponding controls (n=3 technical replicates)