Crystal structure of CYP3A4 bound to an inhibitor

Crystal structure of CYP3A4 bound to an inhibitor Descriptor: Cytochrome P450 3A4, PROTOPORPHYRIN IX CONTAINING FE, {tert-butyl [1-{[([2,2'-bipyridin]-5-yl-kappa~2~N~1~,N~1'~)methyl]amino}-1-oxo-3-(pyridin-4-yl)propan-2-yl]carbamate}bis[2-(quinolin-2-yl-kappaN)phenyl-kappaC~1~]iridium Authors: Sevrioukova, I.F. Deposit date: 2022-10-22 Release date: 2023-02-01 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Dynamic Ir(III) Photosensors for the Major Human Drug-Metabolizing Enzyme Cytochrome P450 3A4. Inorg.Chem., 62, 2023