Tauopathy in the APPswe/PS1ΔE9 mouse model of familial Alzheimer’s disease
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Proteomics on sarkosyl-insoluble proteome of APP/PS1 and human AD brain.
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创建时间：
2019-11-06
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Additional file 3 of A proteomics analysis of 5xFAD mouse brain regions reveals the lysosome-associated protein Arl8b as a candidate biomarker for Alzheimer’s disease
Additional file 3: Supplementary Excel File 1a. DEPs from 5xFAD versus wild-type tissue comparisons in hippocampus and cortex; DEPs were defined using the “pairwise model”; Supplementary Excel File 1b
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Additional file 2: of Quantitative profiling brain proteomes revealed mitochondrial dysfunction in Alzheimerâ s disease
Table S2. iTRAQ quantified human brain proteome of AD individuals and their age-matched control with more than 2 peptides. The data is combined search of three biological replicates. (XLSX 1485 kb)
Figshare2019-01-29 更新90
Additional file 4 of Amyloid fibril proteomics of AD brains reveals modifiers of aggregation and toxicity
Additional file 4: Table S2. List of proteins identified in label-free MS analysis of amyloid fibrils isolated from mouse cortices. Proteins identified with a higher abundance in purified fibrils (N =
Figshare2023-11-21 更新80
Additional file 4: of Integrated proteomics and network analysis identifies protein hubs and network alterations in Alzheimerâ s disease
Table S4. Gene ontology (GO) term enrichment for differentially expressed proteins in AD. The enriched GO terms with associated P values (Benjamini-Hochberg FDR corrected) for biological processes, ce
Figshare2023-06-01 更新100
Dynamic changes in the brain protein interaction network correlates with progression of Aβ42 pathology in Drosophila
Alzheimer’s disease (AD), the most prevalent form of dementia, is a progressive and devastating neurodegenerative condition for which there are no effective treatments. Understanding the molecular pat
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