Ornithodoros Lahorensis Salivary gland LC-MSMS

Ticks are hematophagous vectors of great medical and veterinary importance because they transmit numerous pathogenic microorganisms to humans and animals. The argasid Ornithodoros lahorensis is the vector of tickborne Anaplasma ovis,Crimean-Congo haemorrhagic fever virus and other pathogenic. Tick salivary gland express bioactive molecules that perform key functions in blood feeding and pathogen transmission. To explore new strategies for tick control, in this work we have obtained and compared the salivary gland proteomics of O.lahorensis before and after a blood meal and identified the DEPs regulated after feeding. The proteins were annotated, functionally and their expression levels compared between both physiological conditions (unfed females/males and fed females/males at 24h post-engorgement).