Allosteric SHP2 inhibitors have been shown to be effective against RTKs and certain KRAS mutation-driven tumors in preclinical models. However, the comprehensive effects of SHP2 inhibitors on cellular
snRNA-sequencing from mammary tumors of triple transgenic C57BL/6 mice expressing the MMTV-PyMT oncogene, the MMTV-Cre recombinase and PCBP1(fl/fl) constructs to induce a conditional knock-out of PCBP
THP-1 monocyte were differentiated to macrophage using PMA for 24 hrs, then (THP-1) macrophage were treated with DMSO, Punicalagin, Myricetin or Quercetin for 24 hrs. Transcriptional expression profil
