HINT1 complexed with GS-441524

HINT1 complexed with GS-441524 Descriptor: (2~{R},3~{R},4~{S},5~{R})-2-(4-azanylpyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-(hydroxymethyl)-3,4-bis(oxidanyl)oxolane-2-carbonitrile, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Histidine triad nucleotide-binding protein 1 Authors: Zimberger, C, Ferron, F. Deposit date: 2025-04-08 Release date: 2026-06-03 Last modified: 2026-07-15 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Impact of remdesivir modifications on human HINT1 binding - A structural and functional study in the remdesivir activation pathway. Structure, 34, 2026