Pro-neural transcription factor Six3 has been implicated in neuronal differentiation. We established primary neural stem cell with Six3 overexpression, and utilized CUT&RUN to profile genomic loci bou

NIAID Data Ecosystem50

Identification_of_BCL11A_targets_by_CHIP_Seq. Identification_of_BCL11A_targets_by_CHIP_Seq

乳腺癌干细胞调控

转录因子靶点

We have recently identified BCL11A as a key regulator of mammary stem (MaSC) and progenitor cells. Deletion of BCL11A in MaSC leads to loss of ability of those cells to engraft a cleared mammary fatpa

NIAID Data Ecosystem30

Genome-wide transcriptional targets of KLF15 in human airway smooth muscle

气道平滑肌转录调控

转录因子靶点

We previously demonstrated that the transcription factor, KLF15, is a glucocorticoid-regulated gene that represses primary human airway smooth muscle (ASM) proliferation. Here, we show that KLF15 also

NIAID Data Ecosystem50

ChIP-seq of A673 Ewing sarcoma cells using a specific anti-MYBL2 antibody. ChIP-seq of A673 Ewing sarcoma cells using a specific anti-MYBL2 antibody

尤文肉瘤分子病理

转录因子靶点

Deciphering principles of inter-individual tumor heterogeneity is essential for refinement of personalized anti-cancer therapy. Unlike cancers of adulthood, pediatric malignancies including Ewing sarc

NIAID Data Ecosystem40

Identification of potential downstream targets of GATA3 in the avian utricle

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