Morphological and Physiological Analysis.

Morphological and physiological data from nondiabetic (db/wt) and diabetic (db/db) mouse hearts. Table 1a. Morphological and physiological data are presented in the table. HW, heart weight; tibia length; HW/tibia length ratio, blood glucose levels, and LV EDD (left ventricular end diastolic diameter) are shown. (*p<0.05 vs db/wt) Data represents an n = value 11 mice per group Table 1b. Picture inset visually demonstrates differences in heart morphology of diabetic db/db mouse (right) and nondiabetic db/wt mouse (left). Table 1c. End diastolic pressure volume relationships (EDPVRs) are significantly increased in diabetic (db/db) hearts (right) indicating a stiffer less compliant left ventricle (LV) compared to nondiabetic (db/wt) control hearts (left).