Targeted Manipulation of Cellular RNA m6A Methylation at the Single-Base Level
收藏NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP341054
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资源简介：
We engineered m6A methyltransferase with dCas13-M14 to achieve site-specific editing of m6A. The resultant m6A editors can be programmed with a guide RNA, allowing functional comparison of single site methylation in different mRNA regions. Overall design: Examination of m6A methylation patterns after targeted methylation of YTHDF2-1551, SPEN-3525 and GAPDH-782
创建时间：
2025-01-12
