Total Synthesis of the G2/M DNA Damage Checkpoint Inhibitor Psilostachyin C
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https://figshare.com/articles/dataset/Total_Synthesis_of_the_G2_M_DNA_Damage_Checkpoint_Inhibitor_Psilostachyin_C/2655514
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资源简介：
A concise total synthesis of the G2/M DNA damage checkpoint inhibitor psilostachyin C is reported using a 1,4-addition-aldol condensation-ring-closing metathesis (RCM) strategy. Initial biological studies indicate that psilostachyin C could enhance the sensitivity of the HeLa cell toward camptothecin (CPT) treatment via the activation of the caspase-3 mediated apoptosis pathway.
创建时间：
2016-02-23
