Combined file of supporting figures and tables.

Table S1. Performance comparison of our approach vs the approach NMF on datasets of different lung cancer histological types. Table S2. Comparison of 3-year overall survival (%) of the patient grouping of different clustering methods. Fig. S1. Comparison of the clusters in the literature and the clusters generated by MBI. Fig. S2. Comparison of sample grouping using matrix M vs matrix Y of the ACCstage1 dataset. Fig. S3. MBI helps identify “noise or outlier” sample from the gene expression dataset. (DOCX)