Longitudinal_rsfMRI_TgF344-ADrats_4M_6M

In this project, longitudinal resting-state functional MRI was performed in the TgF344-AD rat model for Alzheimer's Disease. Male rats were scanned at 4-monhts of age and 6-months of age, respectively prior to the onset of amyloid-B plaques and at the early stage of amyloid-B plaque accumulation.

This data set has been used in the following publications:
1. van den Berg M, Adhikari MH, Verschuuren M, Pintelon I, Vasilkovska T, Van Audekerke J, Missault S, Heymans L, Ponsaerts P, De Vos WHet al (2022) Altered basal forebrain function during whole-brain network activity at pre- and early-plaque stages of Alzheimer's disease in TgF344-AD rats. Alzheimers Res Ther 14: 148 Doi 10.1186/s13195-022-01089-2
2. De Waegenaere S, van den Berg M, Keliris GA, Adhikari MH, Verhoye M (2024) Early altered directionality of resting brain network state transitions in the TgF344-AD rat model of Alzheimer's disease. Front Hum Neurosci 18: 1379923 Doi 10.3389/fnhum.2024.1379923