Incidence of uveal melanoma in Ohio.

PurposeTo determine if a greater than expected number of cases (clustering) of uveal melanoma occurred within Ohio for any specific region or time period as compared to others.DesignAnalysis of population database.MethodsOhio Cancer Incidence Surveillance System (OCISS) database (2000–2019) was accessed for the diagnosis of uveal melanoma using the International Classification of Disease for Oncology codes: C69.3 (choroid), C69.4 (ciliary body and iris). Counties within Ohio were grouped by geographic regions (7) and socioeconomic variables. Age- and race-standardized incidence ratios (SIR) were calculated to determine temporal or geographic clustering.ResultsOver the twenty-year period, the total number of uveal melanoma cases reported within Ohio were 1,617 with the overall age-adjusted annual incidence of 6.72 cases per million population (95% CI 6.30–7.16). There was an increase in the incidence of uveal melanoma over 20 years (pConclusionsThere is no evidence of geographic or temporal clustering of uveal melanoma within Ohio from 2000 to 2019.