Stable inducible expression of various GFP-coilin proteins in the presence of endogenous coilin.

Expression denotes the ratio GFP-coilin or mutants thereof to endogenous coilin.†Some cells share different combinations of these phenotypes. Therefore, these percentages do not add up to 100. Phenotypes classified as other include SMN foci lacking coilin (Gems), coilin foci lacking SMN, and coilin micro-foci.N/A = not applicable since the S489D protein is degraded in the stable cell line.Proliferation impact in reflects the change in proliferation rate of a given stable cell line with doxycycline compared to the proliferation rate of the same line in the absence of doxycycline.