Reproducibility Materials, Study-Generated Source Data, and Audit Scripts for an Exploratory Mendelian Randomization and Population-Based Analysis of Diet, Inflammation, and Insomnia-Related Outcomes

This record provides reproducibility materials, study-generated numerical source data, supporting-information files, figure-generation materials, audit utilities, metadata, and a computational-environment specification for the associated manuscript: “Dietary Traits, Systemic Inflammatory Proxies, and Insomnia-Related Outcomes: Exploratory Mendelian Randomization and Population-Based Evidence.” The archived materials include: (1) study-generated source data underlying the principal population-based figures and summary tables; (2) supplementary tables, exposure-mapping metadata, and reporting materials; (3) scripts for file auditing, supplementary-workbook export, source-data-table generation, figure generation, and computational-environment documentation; and (4) repository metadata, provenance files, and reuse documentation. This release is intended to support transparent inspection and reproduction of the deposited source-data tables, figures, and supporting-information exports. Important scope statement: this release does not contain a complete end-to-end rerun pipeline for the upstream high-dimensional Mendelian randomization screen, FinnGen R12/R13 targeted follow-up, NHANES survey-weighted analyses, or CHARLS weighted analyses. Full analytic scripts for these components are being reconstructed, tested against frozen manuscript results, and will be released in a subsequent version of this record after result verification. Third-party source datasets, including GWAS summary statistics, FinnGen resources, NHANES raw files, and CHARLS individual-level data, are not redistributed. Users should obtain these resources directly from their original providers and comply with the relevant access requirements, terms of use, and citation policies. The deposited materials distinguish exploratory genetic prioritisation from population-based association evidence. They do not establish a causal diet–immune–insomnia mechanism, directly confirm flow-cytometry immune-cell phenotypes, or support dietary intervention recommendations.