Summary of significant results from multivariable analyses of peripheral neuropathy in CHARTER subjects.
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*Models shown were adjusted for the following covariates: age, cumulative D-drug exposure, CD4+ T-cell nadir, plasma HIV RNA concentration, self-reported race, protease inhibitor use, HCV status, history of major depression, and 4 ancestry by principal components (for HIV-SN); first five of the same factors plus principal components (for neuropathic pain or neuropathy symptoms).¥Includes presence of paresthesias, loss of sensation, and/or dysesthesias/neuropathic pain.Analyses were performed with no genetic model assumptions (genotypes at each locus were coded as 0, 1, or 2 minor alleles).Abbreviations: HIV-SN, HIV-sensory neuropathy.
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2015-12-02



