Sites identified as Env signatures associated with serum neutralizing breadth and potency using the tree corrected contingency table and CMI approaches.

This table is organized similarly to Table 1.
1All regions are in gp120. CoRbs, coreceptor binding site; V2, second variable region.
2Arrows are used to show the direction of the sequence change that was significant. Thus, in the three amino acids at positions 419–421, the sequence was moving from R, any amino acid, K (R_K) to a sequence that was not R, any amino acid, K (!R_K) in weakly neutralizing sera. [GS]N, means either G or S at position 412 and N at 413.