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Crystal structure of XIAP-BIR3 in complex with a cIAP1-selective SM

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of XIAP-BIR3 in complex with a cIAP1-selective SM Descriptor: (3~{S},6~{S},7~{S},9~{a}~{S})-~{N}-[(4-~{tert}-butylphenyl)methyl]-7-(hydroxymethyl)-6-[[(2~{S})-2-(methylamino)butanoyl]amino]-5-oxidanylidene-1,2,3,6,7,8,9,9~{a}-octahydropyrrolo[1,2-a]azepine-3-carboxamide, E3 ubiquitin-protein ligase XIAP, ZINC ION Authors: Cossu, F, Corti, A, Milani, M, Mastrangelo, E. Deposit date: 2017-11-10 Release date: 2018-08-08 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structure-based design and molecular profiling of Smac-mimetics selective for cellular IAPs. FEBS J., 285, 2018

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2017-11-10
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