The influence of CCL5 to the exprssion profile of tumor associated macrophages (TAMs)

The aim of the dataset was to demonstrate that the gene expression profile of CD11bhiF4/80low TAMs are different from CD11blowF4/80hi TAMs in WT and CCL5-/- BALB/c mice which subcoutinious incubated with CT26 WT or CT26 CCL5 knockdown cell line. Furthermore, we also want to determine the different gene expression profile of CD11bhiF4/80low TAMs which seperated from the colonrectal tumor of WT mice and CCL5-/- mice Overall design: The mRNA profiles of CD11bhiF4/80low TAMs and CD11blowF4/80hiTAMs which isolated from the colonrecatal tumor of WT mice or CCL5-/-mice were generated by deep sequencing, in duplicate, using Illumina HiSeq X Tten.