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Organ-specific Sympathetic Innervation Defines Visceral Functions

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP535795
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We performed single-cell RNA-seq (10x Chromium 3' v.3.1) on dissociated single cell suspensions from mouse (C57BL/6) celiac and superior mesenteric sympathetic ganglia to determine transcriptomic cell types. We identified sympathetic neuron types that specifically innervate unique combinations of visceral organs and control physiological functions. Overall design: We used 20 animals in total, with male and female mice in equal measure. All animals were 7-8 weeks of age.
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2025-01-02
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