AGO2 silences mobile transposons in the nucleus of quiescent cells
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2024-06-05
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A Tudor-domain containing protein, SIMR-1, mediates silencing of piRNA target mRNAs by the Mutator Complex. A Tudor-domain containing protein, SIMR-1, mediates silencing of piRNA target mRNAs by the Mutator Complex
piRNAs play a critical role in the regulation of transposons and other germline genes. In Caenorhabditis elegans, silencing of piRNA target genes is mediated by the Mutator complex, which synthesizes
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Genomic DNA sequence of silkworm cultured cells. Bombyx mori strain:BmN4
PIWI proteins and PIWI-interacting RNAs (piRNAs) play a central role in repressing transposable elements in animal germ cells. It is thought that piRNAs are mainly produced from discrete genomic loci
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Capacity of P transgenes to induce Trans-Silencing Effect.
A large panel of transgenes inserted at various chromosomal locations has been tested for its capacity to induce TSE. Females from lines carrying the tested transgene were crossed with males carrying
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Non-CG methylation is more potent than CG methylation in moss genome regulation [Ppatens RNA-Seq]
Cytosine methylation is commonly targeted to symmetrical CG sites, as well as to non-CGs, such as the symmetrical-CHG and asymmetric-CHH sites in plants (H= A, C or T). Thus far, depletion of CG methy
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The Piwi-piRNA complex initiates transposon silencing via transcription termination factors PNUTS and Senataxin
Transcriptional silencing of transposable elements (TEs) is guided by Piwi and PIWI-interacting RNAs (piRNAs) through the SFiNX complex to induce heterochromatin formation. We previously reported that
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