Large-scale cancer genome projects, such as the Cancer Genome Atlas (TCGA) project, are comprehensive molecular characterization efforts to accelerate our understanding of cancer biology and the disco

NIAID Data Ecosystem50

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype - mouse RNAseq experiments. Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype - mouse RNAseq experiments

胶质母细胞瘤亚型

肿瘤表观遗传学

Glioblastomas in adult patients are classified into four subtypes, IDH, MES, RTK I, and RTK II, based on DNA-methylation and RNA-expression data. Tumour subtype transitions are common during treatment

NIAID Data Ecosystem30

Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype - cell line ChIPseq experiments. Glioblastoma epigenome profiling identifies SOX10 as a master regulator of molecular tumour subtype - cell line ChIPseq experiments

表观遗传调控

胶质母细胞瘤亚型

NIAID Data Ecosystem50

Fosl1 regulates mesenchymal GBM plasticity. Fosl1 regulates mesenchymal GBM plasticity

胶质母细胞瘤亚型

干细胞分子机制

Despite recent advances in genomic profiling techniques, the precise mechanisms controlling GBM subtypes and their plasticity are not fully unraveled. Here,using transcriptomic data of patient derived

NIAID Data Ecosystem30

MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma

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