Tyk2 with compound 8
收藏Protein Data Bank Japan2024-10-30 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6dbk
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资源简介：
Tyk2 with compound 8 Descriptor: 4-({4-[(1S,4S)-5-(cyanoacetyl)-2,5-diazabicyclo[2.2.1]heptan-2-yl]pyrimidin-2-yl}amino)-N-ethylbenzamide, Non-receptor tyrosine-protein kinase TYK2 Authors: Vajdos, F.F. Deposit date: 2018-05-03 Release date: 2018-08-29 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2 Å) Cite: Dual Inhibition of TYK2 and JAK1 for the Treatment of Autoimmune Diseases: Discovery of (( S)-2,2-Difluorocyclopropyl)((1 R,5 S)-3-(2-((1-methyl-1 H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone (PF-06700841). J. Med. Chem., 61, 2018
创建时间：
2018-05-03
