B-Raf Kinase Domain in Complex with an Aminopyridimine-based Inhibitor
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B-Raf Kinase Domain in Complex with an Aminopyridimine-based Inhibitor Descriptor: N-{2,4-difluoro-3-[({6-[(2-hydroxyethyl)amino]pyrimidin-4-yl}carbamoyl)amino]phenyl}propane-1-sulfonamide, Serine/threonine-protein kinase B-raf Authors: Voegtli, W.C. Deposit date: 2012-04-02 Release date: 2013-04-24 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (3.5 Å) Cite: Potent and selective aminopyrimidine-based B-raf inhibitors with favorable physicochemical and pharmacokinetic properties. J.Med.Chem., 55, 2012
创建时间：
2012-04-02
