Transcriptome profile of fibroblasts in chronic thromboembolic pulmonary hypertension. Transcriptome profile of fibroblasts in chronic thromboembolic pulmonary hypertension
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA628645
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资源简介：
The hallmark of chronic thromboembolic pulmonary hypertension (CTEPH) is fibrotic transformation of pulmonary arterial thrombus, leading to mechanical obstruction of pulmonary arteries. We report the transcriptome profile of fibroblasts isolated from pairs of CTEPH thrombus and pulmonary artery adventitia of the same patient. Fibroblasts isolated from CTEPH thrombus demonstrated upregulation of genes associated with the TGF-β pathway indicating that TGF-β upregulation is associated with the intravascular remodeling process. Overall design: RNA-seq of fibroblasts isolated from pairs of CTEPH thrombus and pulmonary artery adventitia from 4 CTEPH patients.
创建时间：
2020-04-27
