Statistical Analysis for all Experiments.

Statistical analysis of each experiment, labelled with the corresponding figure, the genotypes used, and the comparisons between genotypes. D’Agostino & Pearson Normality tests were employed to determine if datasets followed a normal distribution. For comparisons between two independent variables unpaired t-tests were used for parametric datasets, while Mann-Whitney tests were employed for nonparametric datasets. For comparisons between three independent variables ordinary one-way ANOVA tests followed by Tukey’s Multiple Comparisons tests or Holm-Šídák’s Multiple Comparisons tests were used for parametric datasets, while Kruskal-Wallis tests followed by Dunn’s multiple comparisons tests were employed for nonparametric datasets. The p value for each test run is indicated, as is each tests corresponding significance. NS indicates results that are not significant. * p (XLSX)