Late life rapamycin treatment reverses age-related heart dysfunction

ChEBI2013-07-01 更新2026-07-21 收录

衰老相关血管疾病

雷帕霉素治疗

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-48043 数据链接链接失效反馈

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Late life rapamycin treatment reverses age-related heart dysfunction

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2013-07-01

αKlotho regulates age-associated vascular calcification and lifespan in zebrafish. Danio rerio strain:AB | breed:Eukaryotic breed

衰老相关血管疾病

寿命调控

The hormone αKlotho regulates lifespan in mice as knockouts die early of what appears to be accelerated aging due to hyperphosphatemia and soft tissue calcification. In contrast, its overexpression in

NIAID Data Ecosystem80

Crowd4Discovery ventral medial rapamycin-treated cells

神经细胞培养实验

雷帕霉素治疗

Primary ventral medial neuronal culture troubleshooting experiment. These cells are treated with rapamcyin. This experiment is described in the C4D Fall update (link below).

Figshare2016-01-18 更新40

Gene expression data from AKT induced salivary gland tumors. Mus musculus

肿瘤基因表达

雷帕霉素治疗

Rapamycin treatment of AKT induced salivary gland tumors Overall design: Normal tissue (parotid and submandibular), untreated tumor tissue, and tumor tissue treated for 3/14 days

NIAID Data Ecosystem20

Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins

蛋白质氧化还原

衰老相关血管疾病

Reactive protein cysteine thiolates are instrumental in redox regulation. Oxidants, such as hydrogen peroxide (H2O2), react with thiolates to form oxidative post-translational modifications, enabling

NIAID Data Ecosystem40

Supplementary Material for: Endothelium-Specific GTP Cyclohydrolase I Overexpression Restores Endothelial Function in Aged Mice

血管内皮功能

衰老相关血管疾病

This study tested the hypothesis that endothelium-specific GTP cyclohydrolase I (GTPCH I) overexpression (Tg-GCH) restores age-associated endothelial dysfunction in vivo. Aortic GTPCH I expression and

NIAID Data Ecosystem30

Late life rapamycin treatment reverses age-related heart dysfunction

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