T200.2 exome sequencing analysis of PDXs treated by PARP and WEE1 inhibitors

NIAID Data Ecosystem2026-03-10 收录

抗癌药物基因组学

PARP/WEE1抑制剂响应

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA488259 数据链接链接失效反馈

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资源简介：

Examination mutation and copy number variation (CNV) changes treated by PARP and WEE1 inhibitors in PDXs

创建时间：

2018-08-28

gCSI 2019

抗癌药物基因组学

细胞系药物反应预测

gCSI 2019 PharmacoSet (PSet) generated by ORCESTRA. Metadata can be found on ORCESTRA at: http://orcestra.ca/10.5281/zenodo.4737437. An unfiltered version of the gCSI dataset, updated since the public

Zenodo2021-06-21 更新70

Supplementary Table 4 from Integrative Cancer Pharmacogenomics to Infer Large-Scale Drug Taxonomy

抗癌药物基因组学

药物功能分类

Enrichment of DNF drug communities

NIAID Data Ecosystem50

DataSheet1_Preliminary Pharmacogenomic-Based Predictive Models of Tamoxifen Response in Hormone-dependent Chilean Breast Cancer Patients.pdf

抗癌药物基因组学

个体化预测

Tamoxifen (TAM), a selective oestrogen receptor modulator, is one of the most used treatments in oestrogen receptor-positive (ER+) early and metastatic breast cancer (BC) patients. The response to TAM

NIAID Data Ecosystem30

Fig A Hierarchical cluster dendrogram for the pairwise Pearson correlation coefficients of the CGP data; Fig B Heatmap of GI50 correlations for the CGP data; Fig C Glmnet EN regression output for PD-0325901; Fig D Heatmap for CGP drugs that yielded a converged EN model with 10 or more genes; Fig E: Heatmap for minimal EN model of bortezomib; Table A.

抗癌药物基因组学

药物敏感性预测

Pvclust result for GI50 measures in the CGP tumor cells; Table B. Cluster results for EN genes; Table C. GSEA results for minimal EN models of PD_0325901; Table D. GSEA results for the minimal EN gene

NIAID Data Ecosystem50

Additional file 14 of Machine learning approach informs biology of cancer drug response

抗癌药物基因组学

生物过程富集分析

Additional file 14. Supplementary Table S12. Top 20 GO Biological Processes enrichment of elastic-net derived genes for PTX analysis without blood cancers. P-values shown are uncorrected for multiple

Figshare2022-05-17 更新40

T200.2 exome sequencing analysis of PDXs treated by PARP and WEE1 inhibitors

资源简介：

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