Using RNAseq to investigate the underlying genetic mechanisms of disease pathology using Salmonella isolates with high and marginal cell line infectivity

Salmonella enterica subsp. enterica can be divided into multiple serovars based on phenotypic (flagella, O-antigen, capsule) and biochemical properties, as well as now through genetic typing methods (MLST, WGS). Thousands of Salmonella have been sequenced via Illumina and other techniques. With a focus on the Salmonella Typhimurium and Salmonella Enteritidis strains that have been sequenced previously in our study, we now aim to utilize this data and investigate the links between transcriptome and the genetic mechanisms of host adaptation and disease pathology.