A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures
收藏Protein Data Bank Japan2026-04-01 更新2026-04-19 收录
下载链接：
https://pdbj.org/mine/summary/9l62
下载链接
链接失效反馈官方服务：
资源简介：
A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures Descriptor: 1-[6-[azanylidene-[[azanylidene-[[(4-chlorophenyl)amino]methyl]-$l^{4}-azanyl]methyl]-$l^{4}-azanyl]hexyl]-3-[~{N}-(4-chlorophenyl)carbamimidoyl]guanidine, Alpha-(1,6)-fucosyltransferase Authors: Fang, P, Jiang, J. Deposit date: 2024-12-23 Release date: 2026-01-07 Last modified: 2026-04-01 Method: X-RAY DIFFRACTION (3.04 Å) Cite: Exploiting human fucosyltransferase 8 allostery with a covalent inhibitor for core fucosylation suppression. Nat Commun, 17, 2026
创建时间：
2024-12-23
