Flavivirus NS1 protein models
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Four <em>Flavivirus</em> NS1 protein models based on ZIKV-UG (Zika virus from Uganda), ZIKV-BR (Zika virus from Brazil), DENV2 (Dengue virus variant 2), and WNV (West Nile Virus). Due to the crystals for these four NS1 are having missing regions (i.e., X-ray structures with PDB ids 5K6K, 5GS6, 4O6B, and 4O6D, respectively) a homology protocol was applied. Models were built using Modeller 9.24 and default parameters and were selected the structures with the best DOPE score. NS1<sub>ZIKV-UG</sub> and NS1<sub>ZIKV-BR</sub> models are based on the templates with PDB ids 5K6K and 5GS6, respectively. For NS1<sub>DENV2</sub> three templates were used the two complete structures from NS1<sub>ZIKV-UG</sub> and NS1<sub>ZIKV-BR</sub>, and the crystal PDB id 4O6B. For NS1<sub>WNV</sub>, was followed the same strategy as for NS1<sub>DENV2</sub>, but the third template was changed for the crystal PDB id 4O6D. For more details check the SI of https://doi.org/10.1016/j.virusres.2022.198838.
