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Additional file 10: of A pan-cancer analysis of driver gene mutations, DNA methylation and gene expressions reveals that chromatin remodeling is a major mechanism inducing global changes in cancer epigenomes

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Table S8. CDGs associated with significant genome-wide expression changes in one cancer type. Up-regulation is defined as CDGs with p i , k ′ $$ {p}_{i,k}^{\prime } $$ <0.05 and the number of up-regulated genes is larger than the number of down-regulated genes ( G i , k + > G i , k − $$ \left|\ {G}_{i,k}^{+}\right|>\left|\ {G}_{i,k}^{-}\right| $$ ). Down-regulation is defined as CDGs with p i , k ′ $$ {p}_{i,k}^{\prime } $$ <0.05 and the number of up-regulated genes is smaller than the numsber of down-regulated genes ( G i , k + ≤ G i , k − $$ \left|\ {G}_{i,k}^{+}\right|\le \left|\ {G}_{i,k}^{-}\right| $$ ). (XLSX 9 kb)
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Tycko, Benjamin; Wang, Shuang; Rabadan, Raul; In Kim, Kyung; Youn, Ahrim; Shen, Yufeng
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2018-11-07
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