GRE specific DNA-binding polyamide effect on dexamethasone-stimulated lung adenocarcinoma cell line
收藏NIAID Data Ecosystem2026-03-11 收录
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资源简介：
Analysis of dexamethasone-stimulated A549 lung adenocarcinoma epithelial cells treated with a glucocorticoid response (GR) element (GRE) specific DNA binding polyamide. Polyamide designed to target the sequence 5'-WGWWCW-3' and disrupt GR-mediated gene expression. Effects of the GR antagonist mifepristone also examined. A549 cells were treated with compounds for 48 hours before RNA extraction and hybridization on Affymetrix microarrays.
创建时间：
2019-03-25
