Exploring the molecular mechanism of Bushen Huoxue Fang on premature ovarian failure based on transcriptomics and systems biology

Objective: To Explore the mechanism of autophagy in mice with immune premature ovarian failure (POF) and the effect of Bushen Huoxue Fang (BSHXF) Method: POF mice were treated with BSHXF, and estradiol valerate. Then, the ovaries were used for transcriptome sequencing. Overall design: Comparative gene expression profiling analysis of RNA-seq data for POF mice and BSHXF treated mice