Chromosomal translocations are guided by the spatial organization of the genome

ChEBI2012-02-16 更新2026-07-21 收录

染色体易位机制

三维基因组学

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-35519 数据链接链接失效反馈

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Chromosomal translocations are guided by the spatial organization of the genome

创建时间：

2012-02-16

Single-cell DNA replication profiling identifies spatiotemporal developmental dynamics of chromosome organization [HiC-seq]

三维基因组学

胚胎发育表观遗传

In mammals, chromosomes are partitioned into megabase-sized topologically associating domains (TADs). TADs can be in either A (active) or B (inactive) subnuclear compartments, which correspond to earl

NIAID Data Ecosystem90

Hi-C sequencing analysis of wild-type, Ã-actin knockout and Ã-actin hetereozygous mouse embryonic fibroblasts

染色质结构

三维基因组学

Ã-actin is a crucial component of several chromatin remodeling complexes which control chromatin structure and accessibility. The mammalian Brahma-associated factor (BAF) is one such complex that pla

NIAID Data Ecosystem60

Additional file 4 of Identification and utilization of copy number information for correcting Hi-C contact map of cancer cell lines

三维基因组学

癌症基因组分析

Additional file 4. Supplementary Table S3.

Figshare2020-11-07 更新40

Computational prediction of CTCF/cohesin-based intra-TAD (sbTAD) loops that insulate chromatin contacts and gene expression in mouse liver. Computational prediction of CTCF/cohesin-based intra-TAD (sbTAD) loops that insulate chromatin contacts and gene expression in mouse liver

三维基因组学

染色质绝缘

This SuperSeries is composed of the SubSeries listed below, and presents the high throuput sequencing datasets that were generated as part of a larger study that investigates the role of CTCF and cohe

NIAID Data Ecosystem70

Mapping the 3D genome and epigenome in SARS-CoV-2 infected human cells

三维基因组学

病毒-宿主染色质互作

Many viruses can significantly impact host chromatin, but such roles of SARS-CoV-2 are unknown. Here, we characterized the three-dimensional (3D) genome architecture and epigenome landscapes in human

NIAID Data Ecosystem40

Chromosomal translocations are guided by the spatial organization of the genome

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