Gene database of Saccharomyces cerevisiae S288C

Much of genome and modern biology research is done with reductionist approaches using model organisms. Saccharomyces cerevisiae S288C is one such model organism that serves as a platform for investigating eukaryotic cellular processes as well as gene regulation and genetics. Although the genome of S. cerevisiae S288C was sequenced early in the genomic era, its compendium of gene identifier, gene function and gene sequence remain hidden from view of biologists without access to bioinformatic tools. More importantly, the genome of S. cerevisiae S288C is distributed across 16 chromosomes, which makes the task of searching for particular gene and its sequence more difficult. This work sought to ameliorate the above challenge by using an in-house MATLAB software to parse the annotated genome sequence files of S. cerevisiae S288C obtained from Genbank. Both gene identifier and gene sequence were catalogued in an Excel database for all genes in the genome of S. cerevisiae S288C. Overall, the presented gene database should provide ease of access to gene information of S. cerevisiae S288C; thereby, serving as a useful tool in molecular cloning and genome editing studies aiming to understand fundamental cellular processes and biotechnological potential of this important eukaryotic model organism.