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Exploring the downstream genes of PKP2

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NIAID Data Ecosystem2026-03-14 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE140509
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Plakophilin 2 (PKP2), encodes a plakophilin protein that belongs to the member of desmosomal proteins.PkP2 regulates some cell biological functions, but its downstream genes are not clear, so we constructed a stable cell line using H460 cells and identified its downstream target genes by RNA-seq technology To explore the downstream genes of PKP2,we performed RNA-seq to screen after overexpression of PKP2 in H460 cells. We used pSin-puro delivering PKP2 to overexpression of PKP2 in H460 cells.
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2022-11-15
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