Gene expression profile with the p38 inhibitor treatment. Gene expression profile with the p38 inhibitor treatment

Mice bone marrow cells induced dendritic cells were treated with a p38 inhibitor, we used Microgenearry to analyze the dendritic cell-related gene expression, which was induced by a p38 inhibitor. Mice were treated with CAR-T cells with or without p38 inhibitor treatment, we used Microgenearry to analyze the dendritic cell-related gene expression in the tumor environment. Tumor tissues (~100 mg/mouse, 12 days after ACT) were harvested and total RNA was extracted with the RNeasy Mini kit (Qiagen). Overall design: Murine BM cells were cultured and supplemented with mGM-CSF with or without p38 inhibitors. On day 6, semi-adherent cells were collected and total RNA was extracted with the RNeasy Mini kit (Qiagen).