Bone Loss is Ameliorated by Fecal Microbiota Transplantation through SCFA/GPR41/ IGF1 Pathway in Sickle Cell Disease Mice
收藏NIAID Data Ecosystem2026-03-13 收录
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资源简介：
Bone loss is common in sickle cell disease (SCD), but the molecular mechanisms is unclear. Serum insulin-likegrowth factor 1 (IGF1) was low in SCD subjects and SCD mice. To determine if decreased IGF1 associatedwith low bone mass in SCD is due to reduced SCFA production by gut microbiota, we performed reciprocalfecal microbiota transplantation (FMT) between healthy control (Ctrl) and SCD mice
创建时间：
2022-06-28
