We characterized a panel of cancer cells and found that they exhibited chromosome instability (CIN) that was associated with high frequencies of aberrant kinetochore:microtubule attachments. Failure t
In wound-healing system a scratch was generated in subconfluent layers of cells and the repopulation of the denuded areas was measured. High miR-92b expression accelerated wound closure by 63.97% at 2
For the in vitro experiment four photoactivated increments were immersed in a cell culture medium with three different volumes and dilutions: 5.5 mL (Dilution 1 – D1), 11.0 mL (Dilution 2 – D2), or 22
Vaccinia-related kinase 1 (VRK1) and the δ and ε isoforms of casein kinase 1 (CK1) are linked to various disease-relevant pathways. However, the lack of tool compounds for these kinases has significan