Structure of CDK12/CycK in complex with a small molecule inhibitor N-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N-((1r,4r)-4-(quinazolin-2-ylamino)cyclohexyl)acetamide
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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Structure of CDK12/CycK in complex with a small molecule inhibitor N-(4-(1-methyl-1H-pyrazol-4-yl)phenyl)-N-((1r,4r)-4-(quinazolin-2-ylamino)cyclohexyl)acetamide Descriptor: Cyclin-K, Cyclin-dependent kinase 12, MAGNESIUM ION, ... Authors: Klein, M.G. Deposit date: 2018-03-01 Release date: 2018-08-29 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Discovery of 3-Benzyl-1-( trans-4-((5-cyanopyridin-2-yl)amino)cyclohexyl)-1-arylurea Derivatives as Novel and Selective Cyclin-Dependent Kinase 12 (CDK12) Inhibitors. J. Med. Chem., 61, 2018
创建时间：
2018-03-01
